For IBS-C, your doctor may prescribe small doses of an SSRI (selective serotonin reuptake inhibitor) antidepressant, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft).
Their side effects may include nausea, loss of appetite, and diarrhea.
Do antidepressants help IBS symptoms?
Patients who have taken antidepressants for their IBS symptoms have reported significant improvement in their abdominal pain and reduction in other IBS symptoms, such as diarrhea, constipation, bloating, nausea or urgency.
Why do antidepressants help IBS?
Antidepressant medications can reduce the intensity of pain signals going from gut to brain. At times selective serotonin reuptake inhibitors (SSRIs) can help reduce anxiety associated with IBS and can help reduce symptoms of constipation.
Can antidepressants help digestive problems?
Similarly, antidepressants are effective in treating symptoms associated with FGIDs. People who have used antidepressants for their IBS, report significant improvement in abdominal pain as well as a reduction in diarrhea, constipation, bloating, nausea and urgency.
Can Lexapro help IBS?
What antidepressants are used to treat IBS with diarrhea (IBS-D)? Your doctor may recommend another type of antidepressant called an SSRI, which includes citalopram (Celexa), fluoxetine (Prozac), and paroxetine (Paxil), if you have depression along with IBS.