Quick Answer: What Is Stiff Person Syndrome Symptoms?

Stiff-person syndrome (SPS) is a rare neurological disorder with features of an autoimmune disease.

SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise, touch, and emotional distress, which can set off muscle spasms.

Is Stiff person syndrome fatal?

The management of stiff person syndrome is difficult and although success has been reported with the use of plasmapheresis, immunoglobulin, and some cytotoxic agents, most patients continue to follow a relentless and ultimately fatal course.

What does stiff syndrome feel like?

Symptoms. Stiff person syndrome (SPS) is a progressive syndrome characterized by recurrent episodes of severe muscle stiffness, rigidity, and painful spasms in the trunk and limbs.

What causes stiff person syndrome?

Scientists don’t yet understand the complete picture of what causes stiff person syndrome, but research indicates that it is the result of an abnormal autoimmune response in the brain and spinal cord. Autoimmune responses occur when the immune system mistakenly attacks the body.

Can you die from SPS?

About 65 percent of SPS patients are unable to function independently. About ten percent of SPS patients require intensive care at some point; sudden death occurs in about the same number of patients. These deaths are usually caused by metabolic acidosis or an autonomic crisis.

Is Stiff person syndrome curable?

How is stiff person syndrome treated? There’s no cure for SPS. However, treatments are available to help you manage your symptoms. Treatment may also stop the condition from getting worse.

Is there a cure for stiff person syndrome?

Treatment with IVIg, anti-anxiety drugs, muscle relaxants, anti-convulsants, and pain relievers will improve the symptoms of SPS, but will not cure the disorder. Most individuals with SPS have frequent falls and because they lack the normal defensive reflexes; injuries can be severe.